WebMD is a great source for lots of health questions (be sure to check out this slideshow on Cold vs Flu). Here's a table I copied from their website to help answer the question. You'll notice that antibiotics are NOT mentioned as a treatment.
Symptoms
|
Cold
|
Flu
|
Fever | Rare | Characteristic, high (100-102 degrees F); lasts three to four days |
Headache | Rare | Prominent |
General Aches, Pains | Slight | Usual; often severe |
Fatigue, Weakness | Quite mild | Can last up to two to three weeks |
Extreme Exhaustion | Never | Early and prominent |
Stuffy Nose | Common | Sometimes |
Sneezing | Usual | Sometimes |
Sore Throat | Common | Sometimes |
Chest Discomfort, Cough | Mild to moderate; hacking cough | Common; can become severe |
Complications
| Sinus congestion or earache | Bronchitis, pneumonia; can be life-threatening |
Prevention
| Good hygiene | Annual flu shot or FluMist |
Treatment
| Only temporary relief of symptoms | Antiviral drugs (Tamiflu or or Relenza) within 24-48 hours of onset |